Soritmic 20 tablet 80mg Sotalol Соритмик

Soritmic Indications

- ventricular cardiac arrhythmias (tachyarrhythmias) and their prevention with proven effectiveness;

- supraventricular tachyarrhythmias (including atrioventricular / node / paroxysmal tachycardia syndrome, or WPW paroxysm atrial fibrillation);

- prevention of paroxysmal atrial flutter and shimmer after restoration of sinus rhythm;

- arrhythmia caused by excessive circulating catecholamines or increased sensitivity to catecholamines.

Contraindications

Chronic heart failure IIb-III stage (uncontrolled), AV-block II-III degree (in the absence of a functioning pacemaker), sinoatrial block, sick sinus syndrome, cardiogenic shock, severe hypotension, prolongation QT, sinus bradycardia (less than 50 beats / min), acute myocardial infarction, ventricular tachycardia «torsade de pointes», anesthesia, which causes depression of the myocardium, obliterative vascular disease, obstructive airways disease or asthma, hypokalemia and hypomagnesaemia, metabolic acidosis, laryngeal edema, severe allergic rhinitis, untreated pheochromocytoma, renal insufficiency (creatinine clearance <10 mL / min), children's age, lactation, hypersensitivity to the drug and sulfonamides, Raynaud's disease, a rare hereditary intolerance to lactose, lactase deficiency or glucose-galactose malabsorption.

Dosage & Administration

Adults - internally before meals without chewing and drinking plenty of water. In terms of prolongation of QRS, QT prolongation of more than 25% and / or more than 500 ms, lengthening the interval PQ more than 50%, the emergence / increase in the number of attacks of arrhythmia requires correction dosing or discontinuation of therapy.

If tachyarrhythmia recommended starting dose is 40 mh2 twice daily, the maintenance dose is 160-320 mg daily in 2-3 divided doses. If necessary, the dose can be increased to the maximum - 160 mg 3 times a day.

When ventricular cardiac arrhythmia starting dose is 80 mg two times a day. If necessary, the daily dose can be increased to 80 mg 3 times daily or 160 mg 2 times a day. In case of lack of effectiveness of the daily dose can be increased to 480 mg divided into 2 doses. Purpose of this dose ratio needs assessment of potential benefits and risk the possibility of serious adverse reactions (especially proarytmohennyh effects).