Details
Alexan Indications
Therapy of acute non-limb leukemia; acute lymphoblastic leukemia;
acute myeloid leukemia; diffuseV-large cell lymphoma (diffuse hyssocytic lymphoma);
as well as for intracerebral prophylaxis and treatment of leukemic infiltration in the central nervous system.
Contradictions
Hypersensitivity to the active substance or to any of the excipients.
Drug oppression of bone marrow activity (in terms of risk assessment and expected benefits).
During pregnancy, the drug should be administered only after an assessment of the risks and expected benefits.
When breastfeeding, the drug should be stopped
Dosage & Administration
Effective concentration of citarabine in the plasma should be in the range of 0.01 to 0.15 g / ml.
Doses should be determined individually, preferably on the basis of 1 m2 of body surface.

