Details
Zoloft Indications
Zoloft is indicated for the treatment of the following disorders:
• major depressive episodes. Prevention of recurrence of major depressive episodes;
• panic disorder with or without agoraphobia;
• OCD in adults and children aged 6-17 years;
• social anxiety disorder;
• PTSD.
Contradictions
Hypersensitivity to the active substance or to any of the excipients.
Contraindicated use of sertraline with irreversible MAO inhibitors of the action due to the risk of serotonin syndrome (SS) with symptoms such as agitation, tremor and hyperthermia.
Dosage & Administration
Zoloft is taken 1 time a day (morning or evening). Sertraline tablets can be taken with or without food.
Starting treatment
Depression and OCD. Treatment with sertraline should start with a dose of 50 mg / day.
Panic disorder, PTSD and social anxiety disorder. Treatment should be initiated at a dose of 25 mg / day. After 1 week the dose should be increased to 50 mg 1 time per day. It is found that such a dosing regimen reduces the incidence of initially treating side effects typical of panic disorders.
Dose titration
Depression, OCD, panic disorder, social anxiety disorder and PTSD. Patients who did not meet the 50 mg dose, the effect can be achieved with increasing dose. Correction of the dose should be started no earlier than after 1 week of treatment, increasing it gradually by 50 mg at intervals lasting at least 1 week. The maximum dose should not exceed 200 mg / day. Correction of the dose should be no more than 1 time per week, given T½ sertraline, which is 24 hours.
The first manifestation of the therapeutic effect may celebrate within 7 days of treatment. However, to achieve a therapeutic response, usually requires a long period, particularly in patients with OCD.