Details
Novocainamide Indications
Disturbances of cardiac rhythm: ventricular fibrillation, paroxysms of atrial fibrillation or atrial flutter, paroxysmal ventricular tachycardia, ventricular arrythmia.
Contraindications
Hypersensitivity to any component of the drug. Atrioventricular block II and III degree, His bundle branch block, heart failure stage II-III; arrhythmias associated with glycoside intoxication; arrhythmias such as "pirouette"; hypotension; severe renal and hepatic failure, Parkinson's disease, systemic lupus erythematosus, asthma, myasthenia gravis.
Dosage & Administration
The drug is administered orally.
Oral dosage and frequency of administration must be adjusted individually for each patient based on clinical severity assessments primary myocardial disease, age of the patient, renal function.
Adults.
Thus, the initial total daily dose procainamide for oral administration is generally up to 50 mg / kg body weight (14 tablets at a body weight of 70 kg) in divided doses every 3 hours to maintain therapeutic blood levels for young adult patients with normal renal function. For patients older than 50 years in particular, or for patients with renal, cardiac or hepatic insufficiency applied less single dose or longer intervals between doses, which maintains therapeutic blood level of the drug and reduces the risk of dose-dependent adverse reactions. The total daily dose used in divided doses at intervals of 3, 4, or 6 hours and adjusted depending on the patient response.