Melipramin 50 tablets 25mg Imipramine Depression Panic Мелипрамин

Melipramin Indictions

- Depression of any type (with or without anxiety), major depression, depressive phase of bipolar disorder, atypical depression, dysthymia and depression.

- Panic disorder.

- Night enuresis (in children aged 6 years as temporary adjunctive therapy for conditions exclude organic causes of violations).

Contraindications

- Hypersensitivity to the active or any excipient or other tricyclic antidepressants benzodiazepine group.

- Therapy inhibitors of monoamine oxidase (MAO).

- Recent myocardial infarction. Violation conductivity. Arrhythmia heart.

- Mania.

- Severe renal and / or hepatic insufficiency.

- Urinary retention.

- Closure glaucoma (glaucoma vuzkokutova).

Dosage & Aadministration

The daily dose and dosing regimen should be set individually by the nature and severity of the disease. As with other antidepressant therapy, to achieve the desired therapeutic effect is required from 2 to

4 weeks (in some cases - 6-8 weeks). The drug should start with small doses, gradually increasing them to achieve the lowest effective dose and maintenance.

For the elderly and children - dose titration should be performed with caution.

Depression

Patients aged 18-60 years who are in outpatient treatment

The usual starting dose for these patients is 25 mg 1-3 times per day with gradual increase of 150-200 mg / day by the end of the first week of treatment. The usual maintenance dose is 50-100 mg / day.

Patients aged 18-60 years who are hospitalized

In-patients (in particularly serious cases) initial dose is

75 mg / day with gradual increase it to 25 mg per day to 200 mg / day or (in exceptional cases) to 300 mg / day.

Patients aged 60 years

In these patients, treatment should begin with the lowest dose. Subsequently, the initial dose should gradually increase, bringing it in most cases to 50-75 mg / day. It is desirable to achieve the optimal dose for 10 days and sustain it to the end of therapy.

Panic disorder

Patients with this type of disorder, treatment should start with the lowest dose. The temporary strengthening of anxiety at the beginning of antidepressant therapy can be treated or eliminated benzodiazepine dose should be reduced which gradually to zero along with a decrease in anxiety symptoms. Dose Melipraminu® in most cases should gradually increase to 75-100 mg / day (in exceptional cases - up to 200 mg / day).