Details
Dynastat Indications
- Short-term treatment of postoperative pain.
- The decision on the appointment of a selective COX-2 inhibitor should be based on an individual assessment of the patient's risk factors.
Administration
The standard recommended dose or single introduction start - Dinastat 40 mg , optionally in the further preparation is used for every 6-12 hours, 20 mg or 40, but not more than 80 mg / day. Injection should be performed quickly and directly into a vein or an existing intravenous catheter. Injection is performed slowly and deeply into the thickness of the muscle.
Elderly patients. Any dose adjustment of elderly patients (≥65 years) is not required. However, elderly patients with body weight <50 kg, treatment should begin half the standard recommended dose of the drug and reduce Dinastat them the maximum daily dose to 40 mg.
Contradictions
Hypersensitivity to parecoxib or any ingredient of the drug. A history of allergic reactions of any type, especially cutaneous reactions such as Stevens - Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, or known hypersensitivity to sulfonamides.
A history of bronchospasm, urticaria, acute rhinitis, nasal polyps cavity, angioedema, or allergic reactions after ingestion of aspirin or NSAIDs, including other specific inhibitors of COX-2.
Active peptic ulcer or gastrointestinal bleeding.
Serious liver function (blood plasma albumin <25 g / L or score on the scale of Child-Pugh ≥10).
Inflammatory bowel disease.
Congestive heart failure (class II-IV on the NYHA).
The confirmed coronary artery disease, peripheral arterial disease and / or cerebrovascular disease.
Application Dinastata contraindicated for the treatment of pain in the postoperative period after coronary artery bypass grafting (CABG).
III trimester of pregnancy and lactation.
Children under 18 years old.
