Details
Rami Sandoz Indications
Arterial hypertesion; chronic heart failure; chronic heart failure, which is celebrated during the first few days after an acute myocardial infarction; non-diabetic or diabetic glomerular expressed or initial nephropathy; reduction in risk of myocardial infarction, stroke or death in patients with an increased risk factor due to the presence of severe coronary artery disease (with / without myocardial infarction), stroke, peripheral vascular disease history or diabetes mellitus with at least one additional factor for cardiovascular risk (microalbuminuria, hypertension, elevated total cholesterol levels, low HDL cholesterol, smoking).
Dosage & Administration:
Take medication every day at the same time. The tablets should be swallowed whole without chewing, washing down with water. Food does not affect the bioavailability of the drug, so Rami SANDOZ can be taken before, during or after meals.
Tablets can be halved.
Adults.Dose for AH is selected by the physician individually depending on the condition of the patient and the effect on blood pressure.
Rami SANDOZ can be used as monotherapy, or in combination with other antihypertensive agents. The recommended initial dose of ramipril is 2.5 mg 1 time per day. If necessary, the dose may be increased by doubling its every 2-4 weeks. An alternative to increasing doses> 5 mg / day may be further used, for example, calcium antagonists or diuretics.
The usual maintenance dose is 2.5-5 mg / day.
The maximum daily dose for adults - 10 mg.
Treatment of chronic heart failure. The recommended initial dose is 1.25 mg of ramipril once daily 1. Depending on the response of the patient the dose can be increased by doubling its every 1-2 weeks to a maximum daily dose - 10 mg. If necessary, the dose is 2.5 mg ramipril or above, it should be divided into 2 doses.
Treatment after myocardial infarction. After 48 hours following myocardial infarction ramipril recommended initial dose of 2.5 mg 2 times a day for 3 days. If the patient does not tolerate this initial dose, it is recommended to take 1.25 mg 2 times a day for 2 days.
Then, depending on the patient response, dosage may be increased by doubling its every 1-3 days. The maximum daily dose - 10 mg / day, divided into 2 doses.
Contradictions
Hypersensitivity to ramipril, any other ACE inhibitor or to the excipients of the formulation; angioedema in history (hereditary, idiopathic or associated with the use of ACE inhibitors); renal artery stenosis (bilateral or stenosis of the artery of one kidney); severe renal impairment; primary aldosteronism; During pregnancy and breastfeeding; childhood. Rami Sandoz not be used in patients with hypotension or hemodynamically unstable states.
