Hydrochlorothiazide 25 tablets 20mg Hydrochlorotiaside Гидрохлортиазид

Hydrochlorothiazide Indications

- Edema syndrome of different genesis (with congestive heart failure, liver cirrhosis with ascites, nephrotic syndrome, chronic renal failure, premenstrual syndrome, fluid retention in obesity and is caused by medication, such as corticosteroids);

- Hypertension (as monotherapy or in combination with other antihypertensive drugs);

- Symptomatic treatment of neurogenic diabetes insipidus (to reduce polyuria);

- Subcompensated forms of glaucoma;

- Prevention of calcium renal calculus.

Contraindications

- Hypersensitivity to hydrochlorothiazide, other sulfonamides or to any component of the product;

- Severe renal insufficiency (creatinine clearance below 30 ml / min);

- Mechanical obstruction of the urinary tract;

- Severe hepatic insufficiency, hepatic encephalopathy;

- Anuria;

- Gout (severe);

- Hypovolemia;

- Decompensated diabetes;

- A violation of water-salt metabolism (hypokalemia, hypercalcemia, hyponatremia).

Dosage & Administration

The dose of hydrochlorothiazide doctor determines individually. Tablets should be taken after meals.

With the increase in excretion of potassium and magnesium in the treatment may be necessary substitution therapies potassium (K + <3.0 mmol / l) and magnesium.

When edema syndrome initial dose is 25-75 mg (depending on the clinical effectiveness), 1 day or 1 every 2 days. The maximum daily dose - 100 mg.

As Hydrochlorothiazide antihypertensive agent is administered in an initial daily dose of 25-50 mg at one time as a monotherapy or in combination with other antihypertensive drugs.

In some cases, the effective application of the initial dose of 12.5 mg. If necessary, the dose is increased, but the maximum daily dose should not exceed 100 mg per day. Anti-hypertensive effect of hydrochlorothiazide appears within 3-4 days, but for optimal effect may take up to 3-4 weeks. After the treatment antihypertensive effect lasts for about 1 week.

When premenstrual edema usual dose is 25 mg per day, it should be applied in the period from the beginning of the manifestation of symptoms before menstruation.

In nephrogenic diabetes insipidus average therapeutic dose is 50 mg per day. If necessary, the dose may be increased to 100 mg per day.

To prevent the formation of calculus (stones) administered 50 mg 2 times a day.

To reduce intraocular pressure in glaucoma appoint 25 mg 1 every 1-6 days; effect occurs within 24-48 hours.

The daily dose for children aged 2 years is 1-2 mg / kg body weight. Depending on body weight for children from 2 to 12 years - 37,5-100 mg per day. Multiplicity of reception - 1-2 times a day.