Details
Enalapril Indications
Arterial hypertension;
symptomatic heart failure;
asymptomatic left ventricular dysfunction.
Contraindications
Hypersensitivity to ACE inhibitors, diuretics group thiazides, sulfonamides other derivatives, other components of the drug; angioedema in history, caused by the use of ACE inhibitors, hereditary or idiopathic angioedema, severe renal insufficiency (creatinine clearance <30 mL / min) and treatment by dialysis, the clinical condition after kidney transplantation, anuria, primary hyperaldosteronism, renal artery stenosis, liver failure resistant to the treatment of hypercalcemia or hypokalemia, hyponatremia refractory, symptomatic hyperuricemia (gout), concomitant use of enalapril aliskirenom diabetes, pregnant women or women planning to become pregnant
Dosage & Administration
The drug is given to patients in whom blood pressure is not controlled by just one enalapril. The use of a fixed combination of enalapril and hydrochlorothiazide is not suitable for initial therapy and is usually recommended after dosage adjustment of individual components, but the clinical feasibility can immediately move from monotherapy to treat this drug combination.
Dosage and regime are established individually depending on the patient and the severity of hypertension. Treatment should be started at low doses with gradual increase in dosage. Daily dose should be taken in the morning along with plenty of fluids.
