Details
Cordarone Indications
Prevention of relapse:
- Ventricular tachycardia, which is a threat to the life of the patient, the treatment should be started in the hospital in the presence of a constant monitoring of the patient;
- Symptomatic ventricular tachycardia (documented) that leads to disability;
- Supraventricular tachycardia (documented) that requires treatment, and in cases where other drugs have no therapeutic effect or are contraindicated;
- Ventricular fibrillation.
Treatment of supraventricular tachycardia: slowing down or reducing atrial fibrillation or flutter.
Coronary heart disease and / or dysfunction of the left ventricle.
Contraindications
Sinus bradycardia, sinoatrial heart block in the absence of endocardial pacemaker (artificial pacemaker).
Sick sinus syndrome in the absence of endocardial pacemaker (risk of sinus node stops).
Violation high degree atrioventricular conduction in the absence of endocardial pacemaker. Thyroid dysfunction.
Known hypersensitivity to iodine, amiodarone or to one of the excipients.
The combination of drugs that can cause paroxysmal ventricular tachycardia of torsades de pointes:
- Class Ia antiarrhythmic agents (quinidine, hidrohinidyn, dyzopiramid);
- Class III antiarrhythmic drugs (sotalol, dofetilide, ibutylid);
- Other medicines such as arsenic, bepridil, cisapride, dyfemanil, dolasetron (intravenously), erythromycin (iv) mizolastyn, Vincamine (intravenously), moxifloxacin, spiramycin (IV), toremifene, some antipsychotics (see. Section "Interaction with other medicinal products and other forms of interaction").
Dosage & Administration
The initial treatment. The usual recommended dose - 200 mg (1 tablet) 3 times daily for 8-10 days. In some cases, initial treatment using higher doses (4-5 tablets a day), but always - in a short period of time and under ECG control.
Supportive treatment. It should use the lowest effective dose. Depending on patient response to the drug maintenance dose for adults ranges from ½ tablets per day (1 tablet every 2 days) to 2 tablets per day.