Details
Zolmigren Indications
Treatment of migraine accompanied by aura (visual, auditory, motor and mental disorders) and without aura.
Dosage & Administration
the drug is not intended for use in the prophylaxis of migraine attack. Zolmigren recommended to apply as early as possible after the onset of a migraine attack.
Adults appoint 1 tablet (2.5 mg zolmitriptan). In the absence of effect or recurrence of pain possible re taking 1 pill. If necessary, repeat the dose can be taken no earlier than 2 hours after the first dose. In inefficiency permitted dose of 2.5 mg single dose increasing to 5 mg (maximum single dose). The maximum daily dose - 15 mg.
For patients with mild to moderate hepatic dysfunction correction dose is not required. For patients with severe hepatic dysfunction the daily dose should not exceed 5 mg.
When creatinine clearance> 15 mL / min the dose should not be corrected.
Contradictions
Increased individual sensitivity to the drug.
Severe hypertension and uncontrolled mild increase in blood pressure. Ischemic heart disease, including myocardial infarction. Vasospastic angina (Prinzmetal angina).
Cerebrovascular disorders, and transient ischemic attack (TIA) in history. Creatinine clearance <15 mL / min. WPW-syndrome and arrhythmias associated with other cardiac additional routes of. Simultaneous administration of ergotamine, derivatives of ergotamine, sumatriptan, naratriptan or other agonists of 5HT1B / 1D receptors. Peripheral vascular disease. Elderly (> 65 years) age.