Details
Propanorm Indications
- Tachyarrhythmia, including tachycardia involving AV-knot, supraventricular tachycardia syndrome Wolff-Parkinson-White (WPW), as well as forms of paroxysmal atrial flutter / atrial fibrillation;
- Severe symptomatic ventricular tachyarrhythmias.
Contraindications
● Hypersensitivity to the active substance or to any component of the product;
● AV-block II and III level in the absence of a pacemaker;
● sinoatrial block;
● right bundle branch block together with the blockade of one of the left bundle branch
Branch block (bifastsykulyarna block) in the absence of a pacemaker;
● uncontrolled chronic heart failure (left ventricular ejection fraction <35%);
● cardiogenic shock (except arrhythmogenic);
● severe symptomatic sinus bradycardia (heart rate <50 beats / min);
● sick sinus syndrome;
● hypotension (in terms of arterial systolic blood pressure <90 mmrt. In.);
● hypokalemia, hyperkalemia (potassium necessary correction of the exchange before the
treatment); another electrolyte imbalance;
● severe chronic obstructive pulmonary disease;
● bronchospasm;
● myasthenia gravis;
● severe liver failure;
● renal dysfunction;
● revealed Brugada syndrome.
The drug is contraindicated in the first 3 months after acute myocardial infarction, and in patients with low cardiac output (except for patients with atrial fibrillation, which is life threatening).
Dosage & Administration
Injected intravenously. Propanormom recommended therapy under the supervision of a doctor experienced in treating arrhythmias. Individual maintenance dose should be determined under cardiological observation conditions, including monitoring of ECG (complex QRS, PR interval and QTc), blood pressure control and performance of the circulatory system.
Treatment should begin with the introduction of lower doses. The desired therapeutic effect often occurs after a dose of 0.5 mg / kg. The usual therapeutic single dose of 1 mg / kg body weight (with an average body weight of 70 kg corresponding to 20 ml). If necessary, a single dose can be increased to 2 mg / kg (with an average body weight of 70 kg corresponds to 40 ml).
Intravenous injection should be administered slowly for 3-5 minutes. The interval between
injections - at least 90-120 minutes.