Nivalin injection solution 10ampl 1ml 1mg & 2,5mg /ml Galantamine hydrobromide Nervous disorders Нивалин

 Nivalin Indications

Neurology

- peripheral nervous system diseases (polyradiculitis, radiculoneuritis, neuritis, polyneuritis, polyneuropathy);
- treatment of conditions associated with damaged anterior horns of the spinal cord (after polio myelitis, spinal muscular atrophy);
- cerebral Palsy (state after brain stroke, cerebral palsy, after CNS injury);
- disorders of neuromuscular synapses (myasthenia gravis, muscular dystrophy);
- cognitive impairment in various diseases of the central nervous system (trauma, intoxication, multiple sclerosis, autism).

Anaesthesia and Surgery 

- to eliminate the action of non-depolarizing neuromuscular blocking agents;
- treatment of postoperative paresis of the small intestine and bladder.

- iontophoresis neurological disorders of the peripheral nervous system, bedwetting.

Toxicology

- poisoning anticholinergics.

Contraindications

- Hypersensitivity to the active substance galantamine hydrobromide or to any of the excipients of the drug;

- Severe renal insufficiency (creatinine clearance below 9 ml / min);

- Severe hepatic insufficiency (grade above 9 on a scale Child-Pugh (Child-Pugh));

Dosage & Administration

Dosage and duration of treatment with galantamine depend on the nature and course of the disease and the effectiveness of therapy.

Neurology. Nivalin in the form of p-ra injection used for the treatment of short as well as for patients who can not be administered orally. As soon as possible move to the use of Nivalin in the form of tablets.
Adults. Typically Nivalin rr injection using a dose 0,03-0,28 mg / kg body weight.
The recommended initial dose - 2.5 mg / day. The daily dose is gradually increased at intervals of 3-4 days to 2.5 mg, divided into 2-3 equal doses.

The maximum single dose for adults is 10 mg of p / k, and the maximum daily dose - 20 mg.

Children:

children under the age of 1 year - 2 years: 0.25-1 mg (0.02-0.08 mg / kg); over 3 years: 0,03-0,28 mg / kg; 3-5 years: 0.5-5 mg; 6-8 years: 0,75-7,5 mg; 9-11 years: 1-10 mg; 12-15 years: 1,25-12,5 mg; 15 years and under: 1,25-15 mg.