Moxogamma 30 tablets 0,2mg & 0,3mg & 0,4mg Hypertension treatment Moxonidine Моксогамма

Moxogamma Indications

Hypertension.

Contraindications

- Hypersensitivity to any component of the drug;

- Sick sinus syndrome or sinoatrial heart block;

- Bradycardia (less than 50 beats per minute at rest);

- Atrioventricular block second or third degree;

- heart failure.

Dosage & Administration

Adults. Treatment should be initiated at the lowest dose of moxonidine - 0.2 mg per day. If insufficient therapeutic effect after 3 weeks the dose can be increased to 0.4 mg. This dose can be taken for 1 time (morning) or divided into 2 doses (morning and evening). If over the next 3 weeks the results are not satisfactory, the dose can be increased up to 0.6 mg, taking 2 hours in the morning and evening. A single dose of 0.4 mg moxonidine and a daily maximum dose of 0.6 mg moxonidine not be exceeded. The dose should be individualized depending on patient response.

The drug can be taken regardless of food intake. The tablet should be taken with plenty of fluids.

Elderly patients. If there is renal failure, the dosage is the same as for adults.

Kidney failure. For patients with moderate renal impairment (glomerular filtration rate> 30 ml / min but <60 ml / min), and for patients who are on hemodialysis initial dose should not exceed 0.2 mg if necessary dose can be increased. Patients with severe renal impairment (glomerular filtration rate <30 mL / min) moxonidine is contraindicated.

Liver failure. For patients with hepatic impairment clinical data available. However moxonidine not undergo metabolism in the liver, a significant effect on its pharmacokinetics are not expected. Therefore dosage for patients with weak moderate hepatic impairment is recommended is the same as for adults. Reception preparatune interrupt suddenly, as the possibility of rebound hypertension as a "cancellation effect" can not be completely excluded. The drug should be discontinued for 2 weeks, gradually reducing the dose.