Details
Viraxa Indications
Chickenpox virus (VZV), infection - shingles:
- Treatment of herpes and ophthalmic herpes for immunocompetent adults
- Treatment of herpes in immunocompromised adults
Herpes simplex virus (HSV), infections - genital herpes:
- Treatment of the first manifestations and recurrences of genital herpes in immunocompetent patients;
- Treatment of recurrences of genital herpes in adults with weakened immunity;
- Suppression of recurrent genital herpes in immunocompetent patients and in immunocompromised patients.
Contraindications Dosage and administration
Hypersensitivity to famciclovir or to other components of the drug, as well as hypersensitivity to penciclovir.
Dosage and administration
Because the systemic bioavailability of penciclovir did not change when famciclovir was taken with food, famciclovir can be used with or without food.
Shingles in immunocompetent patients
500 mg 3 times a day for 7 days. Treatment gives better results if it is started immediately after the rash appears.
Shingles in immunocompromised patients
500 mg 3 times a day for 10 days. It is recommended to start treatment immediately after the appearance of rashes.
Genital herpes in immunocompetent patients
The first manifestation of genital herpes
250 mg 3 times a day for 5 days. It is recommended to start treatment immediately after the onset of genital herpes.
Recurrence of genital herpes
125 mg 2 times a day for 5 days. It is recommended to start treatment in the prodromal period (tingling, itching, burning, pain) or immediately after the onset of genital herpes.
Recurrence of genital herpes in immunocompromised patients
500 mg 2 times a day for 7 days. It is recommended to start treatment in the prodromal period (tingling, itching, burning, pain) or immediately after the appearance of rashes.
Suppression of recurrent genital herpes in immunocompetent patients
250 mg 2 times a day. The duration of treatment depends on the severity of the disease, but treatment should be discontinued after 12 months of continuous therapy in order to reassess the severity and frequency of relapses. The minimum revaluation period should cover two relapses. A dose of 500 mg twice a day was effective for immunocompromised patients.
Suppression of recurrent genital herpes in immunocompromised patients
500 mg 2 times a day.
Dosage for patients with impaired renal function
Because decreased clearance of penciclovir is associated with impaired renal function, consistent with changes in creatinine clearance, special attention should be paid to dosing for patients with impaired renal function.
