Details
Piroxicam Indications
Symptomatic treatment of osteoarthritis, rheumatoid arthritis or ankylosing spondylitis.
Because of the safety profile of piroxicam is not a first-choice, if shown the use of other nonsteroidal anti-inflammatory or anti-rheumatic drugs. The decision to appoint piroxicam should be based on an individual assessment of the overall risk to the patient.
Contraindications
- Ulcer gastrointestinal bleeding or perforation in history;
- Gastrointestinal disease in history, which may lead to bleeding, such as ulcerative colitis, Crohn's disease, cancer of the gastrointestinal tract or diverticulitis;
- Active peptic ulcer, inflammatory gastrointestinal disease or gastrointestinal bleeding;
- Concomitant use with other NSAIDs (NSAIDs), including selective COX-2 inhibitors and acetylsalicylic acid at analgesic doses;
- Concomitant use of anticoagulants;
- Previous serious allergic reactions of any type, especially cutaneous reactions such as erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis;
- Hypersensitivity to the active substances or auxiliary, transient skin reactions (regardless of severity) in response to the use of piroxicam and other nonsteroidal anti-inflammatory and anti-rheumatic drugs and other drugs;
- Severe heart failure;
- Severe renal or hepatic impairment;
- Use of aspirin and other NSAIDs in patients with NSAID induced development of asthma, nasal polyps, angioedema;
- Treatment of perioperative pain in coronary artery bypass grafting.
Dosage & Administration
The primary purpose piroxicam should be made by a doctor who has experience in diagnostic evaluation and treatment of patients with inflammatory or degenerative rheumatic diseases. The maximum recommended dose is 0.02 g
Side effects can be reduced by using the minimum effective dose for the shortest time required for treatment.