Details
Nystatin belongs to a group of polyolefinic antimycotic antibiotics which are highly effective against yeast-like Candida fungi. The antibiotic possesses a double bond which exerts high level of affinity to the phytosterole structures of the fungal cell membrane, which in turn promotes formation of a channels which start the uncontrolled transport of electrolytes through the membrane cell increase in osmolarity leads to fungal cell death. Resistance for nystatin is formed slowly.
INDICATIONS:
The drug is used in treatment and prophylaxis of gastrointestinal candidosis. Prophylaxis of fungal infections before and after surgery on the gastro-intestinal tract.
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