Details
Levicitam Indications
- monotherapy (the drug of first choice) in the treatment of:
partial seizures with secondary generalization or without children and adults over the age of 16 years who first diagnosed epilepsy.
- In the combined therapy in the treatment of:
partial seizures with secondary generalization or without children and adults over the age of 4 years, patients with epilepsy;
myoclonic seizures in adults and children over the age of 12 years, patients with juvenile myoclonic epilepsy;
primary generalized convulsive (tonic-clonic) seizures in adults and children over the age of 12 years, patients with idiopathic generalized epilepsy.
Contradictions
Hypersensitivity to levetiracetam or other pyrrolidone derivatives, as well as any components of the drug; children under 4 years of age (safety and efficacy have not been established); advanced age (65 years); severe liver function; renal insufficiency.
Dosage & Administration
Tablets are taken orally with a glass of plenty of fluids, regardless of the meal. The daily dose is divided into two identical reception.
Monotherapy in adults and children over the age of 16 years should start with a dose of 250 mg 2 times a day. After 2 weeks the dose may be increased to an initial therapeutic - 500 mg 2 times a day. The maximum daily dose of 1500 mg 2 times a day, that is, should not exceed 3 years
In the combined therapy in children older than 4 years of treatment should be started at a dose of 10 mg / kg body weight 2 times a day. Increasing daily dose of 20 mg / kg body weight may be carried out every two weeks to achieve the recommended daily dose - 30 mg / kg body weight two times a day. If necessary, the daily dose can be reduced. It is recommended to use the minimum effective dose.
Recommended doses, depending on the body weight of the child:
children weighing <25 kg of levetiracetam administered in another dosage form with the ability to lower dosing;
children weighing 25-50 kg: initial dose - 250 mg 2 times a day; maximum - 750 mg 2 times a day;
Children weighing> 50 kg dosing is carried out according to the scheme described for adults.