Details
Diocor Indications
Hypertension, after failure of monotherapy.
Dosage & Administration
the recommended dose - 1 tablet 1 time per day. In the clinical setting can be employed Tablets containing 80 mg valsartan and 12.5 mg of hydrochlorothiazide, or in case of failure of the dosing - tablets containing 160 mg valsartan and 12.5 mg of hydrochlorothiazide.
The maximum antihypertensive effects achieved within 2-4 weeks of application.
For patients with slight and moderate renal impairment (creatinine clearance of> 30 ml / min) dose adjustment is required. For people with mild to moderate hepatic insufficiency nebiliarnogo origin and without cholestasis the dose adjustment is required.
The duration of the drug determines the individual physician.
Contradictions
Hypersensitivity to any component of the drug; During pregnancy and breastfeeding; severe liver, biliary cirrhosis and cholestasis; anuria, severe renal dysfunction (creatinine clearance <30 mL / min); hypokalemia, hyponatremia, hypercalcemia, hyperuricemia.