Details
Cardura Indications
Arterial hypertension
The drug is indicated for the treatment of hypertension and for the majority of patients it can be used to control blood pressure as monotherapy. In case of failure of monotherapy to treat patients with hypertension drug can be used in combination with thiazide diuretics, β-blockers, adrenergic receptors, calcium channel blockers and ACE inhibitors.
BPH
The drug is indicated for the treatment of urinary obstruction and symptoms associated with BPH. The drug can be administered to patients with BPH, both in the presence of hypertension and blood pressure at a normal level.
Dosage & Administration
Cardura medication can be taken with morning and evening.
AH
The drug should be used 1 time per day. The initial dose is 1 mg to minimize the risk of orthostatic hypotension and / or syncope. After 1-2 weeks of initial therapy dose can be increased to 2 mg, and then, if necessary - up to 4 mg. Most of the patients response to treatment is observed when using the drug in a dose ≤4 mg. If necessary, the dose can be increased to 8 mg or up to the maximum recommended dose - 16 mg.
BPH
The recommended initial dose of the drug is Cardura 1 mg 1 time a day, in order to minimize the risk of orthostatic hypotension and / or syncope. Depending on the individual characteristics of the patient and urodynamics BPH symptoms, the dose can be increased to 2 mg, 4 mg to then and up to the maximum recommended dose - 8 mg. The recommended dose range selection is 1-2 weeks. The usual recommended dose is 2-4 mg / day.
Elderly patients should use the usual dose for adults.
Patients with impaired renal function should be used the usual dose for adults, since the pharmacokinetic parameters of the drug in kidney function do not change.
Contradictions
Cardura use of the drug is contraindicated in the following categories of patients:
- hypersensitivity quinazoline derivatives (e.g. prazosin, terazosin, doxazosin) or any of the excipients of the formulation;
- cases of orthostatic hypotension in history;
- BPH and concomitant obstruction of the upper urinary tract, chronic urinary tract infections and the presence of stones in the bladder;
- with arterial hypotension (applies only to patients with benign prostatic hyperplasia).
