Details
Carboplatin Indications
- ovarian cancer
- testicular cancer
- lung cancer
- bladder cancer
- cervical cancer
Contradictions
- disorders of renal function (glomerular filtration rate <30 ml / min);
- hypersensitivity to carboplatin and other platinum compounds in history;
- severe forms of myelosuppression;
- hearing impairment;
- acute infections;
- bleeding tumors and other significant blood loss;
- simultaneous use of yellow fever vaccine.
Dosage & Administration
The recommended dose of the drug for previously untreated adults with normal renal function is 400 mg / m2 body surface area.
The drug is administered by short intravenous infusions (15-60 minutes duration).
The course should be repeated no earlier than 4 weeks after the previous injection and / or until the neutrophil content is 2 × 109 / l and the platelet content is 100 × 109 / l.