Details
Cordinorm Indications
- hypertension;
- coronary heart disease (angina);
- chronic heart failure with left ventricular systolic dysfunction in combination with ACE inhibitors, diuretics, if necessary - cardiac glycosides.
Contraindications
Hypersensitivity to bisoprolol or any other drug. Acute heart failure or heart failure in a state of decompensation requiring inotropic therapy. Cardiogenic shock. Atrioventricular block II and III level. Sick sinus syndrome. Severe sinoatrial block. Symptomatic bradycardia (heart rate (HR) of less than 60 beats per minute). Symptomatic hypotension (systolic blood pressure below 100 mm Hg). Severe bronchial asthma or severe chronic obstructive pulmonary disease. Late stage of infringement peripheral circulation, Raynaud's disease. Pheochromocytoma, not treated. Metabolic acidosis.
Dosage and administration
The drug should be taken in the morning is not liquid, regardless of the meal, washed down with a small amount of liquid.
Treatment of hypertension and stable angina / stenocardia
When hypertension and stable angina - initial dose of 2.5-5 mg / day, the average daily dose - 5-10 mg, the maximum daily dose - 20 mg.
Treatment of chronic heart failure.
In chronic heart failure drug is prescribed to patients with moderate and severe heart failure with reduced systolic function (ejection fraction ≤35% by echocardiogram data), we are in a position to stabilize without exacerbation during the past 6 weeks.
The initial dose is 1.25 mg 1 time per day during the first week (bisoprolol preparations are used with such dosing). During the 2nd week of receiving the prescribed 2.5 mg / day. During the third week of the therapeutic dose of 3.75 mg / day (bisoprolol preparations are used with such dosing). From the 4th week 8th reception taking 5 mg. Thereafter, the dosage was increased to 7.5 mg (8 th to 12 th week). After 12 weeks of treatment is assigned the maximum daily dose - 10 mg. Increasing the dose is adjusted rates of heart rate, blood pressure and general condition of the patient.
The maximum dose - 10 mg / day.
