Details
CLABAX INDICATIONS
treatment of infections caused by susceptible organisms clarithromycin:
- lower respiratory tract infections (bronchitis, pneumonia);
- upper respiratory tract infections (sinusitis, pharyngitis);
- skin and soft tissue infections (folliculitis, erysipelas).
APPLICATION
Clarithromycin recommended dose for adults and children over the age of 12 years is 500 mg 1 time per day during the meal. In severe infections the dose can be increased to 1000 mg 1 time per day (2 tablets of 500 mg).
The duration of treatment is from 5 to 14 days, except for community-acquired pneumonia and sinusitis, which require a treatment for 6-14 days. The tablets should be swallowed whole without chewing.
Use in patients with renal insufficiency: this form of the drug is not used in patients with severe renal insufficiency (creatinine clearance <30 mL / min), because it does not adequately reduce the dose. Such patients need to use a tablet of clarithromycin immediate-release 250 mg. In patients with moderate renal impairment (creatinine clearance of 30-60 ml / min) dose reduced by 50% to a maximum dose of clarithromycin - 1 depot tablet per day.
CONTRAINDICATIONS
Hypersensitivity to macrolide antibiotics, and other ingredients.
Concomitant use of clarithromycin and any of such means: astemizole, cisapride, pimozide, terfenadine, ergotamine, dihydroergotamine, derivatives horns. Patients with creatinine clearance <30 mL / min (since this form does not allow the drug to reduce the dose below 500 mg / day); hypokalemia (prolongation of the Q-T interval). During pregnancy and breastfeeding; age up to 12 years.