Details
Agapurin SR Indications
Extending silent walk distance in patients with chronic peripheral artery occlusion lesions in stage IIb by Fontaine (intermittent claudication) when other measures such as training moves, angioplasty and / or recovery procedures can not be carried out or not shown.
Inner ear dysfunction caused by circulatory disorders (including tuhovuhist and sudden hearing loss).
Contraindications
Hypersensitivity to pentoxifylline, other methylxanthine derivatives or to any of the ingredients of the drug.
Acute myocardial infarction.
Stroke or other clinically significant bleeding.
Ulcers of the stomach and / or intestines.
Hemorrhagic diathesis.
Hemorrhage in the retina.
If the pentoxifylline treatment is bleeding in the retina, the use of drug should be immediately discontinued.
Dosage & Administration
Dosage of 400 mg / 600mg SR Ahapurin is established by physician in view of the individual patient.
Tablets prolonged action should be swallowed whole (not liquid), drinking plenty of water. Treatment duration should install doctor depending on the clinical condition of individual patients.
Chronic occlusive peripheral arterial disease in stage IIb by Fontaine (intermittent claudication).
If not used for other dosage 1 tablet prolonged drug AhapurynT SR 400 mg 3 times daily / 600 mg 2 times daily (1200 mg pentoxifylline per day).
For patients with low or unstable blood pressure level required dose adjustment.
Dosage for patients with impaired renal function (creatinine clearance less than 30 ml / min) should be selected, taking into account individual tolerance.
For patients with severe hepatic dysfunction dose reduction is required. The decision to reduce the dose taken by the doctor, which in each case must take into account the severity of the disease and tolerability.
