Details
Linezolidin Indications
Treatment of infections caused by susceptible strains of anaerobic or aerobic gram-positive bacteria, including infections, accompanied by bacteremia, such as:
- Nosocomial (hospital) pneumonia
- Community acquired pneumonia
- Infections of skin and soft tissues
- Infections caused by enterococci, including vancomycin-resistant strains
Enterococcus faecium and faecalis.
If infection pathogens include Gram-negative bacteria, clinically shown combination therapy appointment.
Contraindications
Hypersensitivity to linezolid or any other component of the drug. Linezolidyn should not be used in patients taking drugs that suppress monoamine oxidase A and B (eg phenelzine, izokarboksazyd, selegiline, moclobemide) or within two weeks after receiving such drugs.
Dosage and administration. Before using the drug to be done skin test for sensitivity to linezolid.
Patients whose treatment was started with the purpose Linezolidynu as intravenous infusion may be transferred to treatment with linezolid in a form for oral administration. In this case, the selection of dose is not needed because the bioavailability of linezolid when taken internally is almost 100%.
Overdose. In case of overdose, symptomatic treatment is indicated with the activities in support of glomerular filtration. In hemodialysis excreted from the body about 30% of the dose of the drug.