Lasix (Furosemide) 40mg 45 tablets Лазикс

Lasix Indications

• Edema in chronic congestive heart failure (if treatment with diuretics is required).

 • Edema in chronic renal failure.

 • Acute renal failure, including during pregnancy or childbirth.

 • Edema in nephrotic syndrome (if treatment with diuretics is required).

 • Edema in liver disease (if necessary - to supplement treatment with aldosterone antagonists).

 • Hypertension.

Contraindications

Hypersensitivity to furosemide or other components that make up the drug.

Patients allergic to sulfonamides (such as antibiotics or sulfonylureas sulfonamidni) can be cross-sensitivity to furosemide.

Hypovolemia or dehydration.

Renal insufficiency in anuria as if there is no therapeutic response to furosemide.

Renal failure due to poisoning by nephrotoxic or hepatotoxic drugs.

Severe hyponatremia.

Dosage & Administration

The dosage regimen is set by the doctor individually, depending on the severity of disorders of water-electrolyte balance, the amount of glomerular filtration, the severity of the patient's condition. In the process of drug administration, the indicators of water-electrolyte balance should be adjusted taking into account diuresis and the dynamics of the general condition of the patient. The drug should be used on an empty stomach.

 For adults, the recommended maximum daily dose of furosemide is 1500 mg.

 Special dosing recommendations.

 Dosage for adults is generally based on the application of the following recommendations.

 • Edema in chronic congestive heart failure.

 The recommended starting dose of the drug for oral administration is 20-50 mg per day. If necessary, the dose can be adjusted depending on the patient's therapeutic response. It is recommended to take a daily dose divided into 2 or 3 doses.

 • Edema in chronic renal failure.

 The natriuretic effect of furosemide depends on a number of factors, including the severity of renal failure and sodium balance. Thus, it is impossible to accurately predict the effectiveness of the dose. For patients with chronic renal failure, the dose should be carefully titrated to ensure gradual initial fluid loss. For adult patients, this means using a dose that results in a daily weight loss of approximately 2 kg (approximately 280 mmol Na +).

 The recommended initial daily dose for oral administration is 40-80 mg. If necessary, the dose can be adjusted depending on the patient's therapeutic response. The total daily dose can be administered once or divided into 2 doses. For patients on hemodialysis, the total daily oral dose is 250-1500 mg.

 • In acute renal failure, hypovolaemia, hypotension, and significant electrolyte and acid-base imbalance should be compensated for before initiating furosemide.

 It is recommended to switch from intravenous to oral administration as soon as possible.

 • Edema in nephrotic syndrome.

 The recommended starting dose for oral administration is 40-80 mg per day. If necessary, the dose can be adjusted depending on the patient's therapeutic response. The total daily dose can be administered once or divided into several doses.

 • Edema in liver disease.

 Furosemide should be used as an adjunct to aldosterone antagonist therapy in cases where the use of aldosterone antagonists alone is insufficient. To prevent complications such as orthostatic hypotension or electrolyte and acid-base imbalance, the dose should be carefully titrated to ensure gradual initial fluid loss. For adult patients, this means using a dose that results in a daily weight loss of approximately 0.5 kg.

 The recommended initial daily oral dose is 20-80 mg. If necessary, the dose can be adjusted depending on the patient's therapeutic response. The total daily dose can be administered once or divided into several doses. If intravenous administration is absolutely necessary, the initial single dose is 20-40 mg.