Endoxane 50 tablets 50 mg cyclophosphamide breast cancer Эндоксан

Endoxane Indications

During a regime of combined chemotherapy with other antineoplastic drugs or in the form of monotherapy of diseases:

- adjuvant therapy for breast cancer after tumor resection or mastectomy;
- palliative therapy for metastatic breast cancer;
- autoimmune diseases with life-threatening progression, namely, the severe progressive forms of Waggene's lupus nephritis and granulomatosis.

Contradictions

- hypersensitivity to cyclophosphamide or to any of the excipients;
- severe bone marrow dysfunction (especially in patients previously treated with cytotoxic agents and / or radiotherapy);
- inflammation of the bladder (cystitis), urinary tract infections;
- acute urothelial toxicity after treatment with cytotoxic drugs and / or radiotherapy;
- disorders of urine outflow;
- active infections.

Dosage & Administration

Dosage should be selected individually for each patient.

Doses and duration of treatment and / or treatment intervals are dependent on therapeutic indications, combination therapy regimens, general patient health, organ function and laboratory monitoring results (especially blood cell monitoring).