Depakin Chrono 100 tablets 300mg Valproic acid Депакин Хроно Epileptic seizures

Depakin Chrono Indications

For adults, as monotherapy or in combination with other antiepileptic drugs:
- For the treatment of generalized seizures (clonic, tonic, tonic-clonic seizures, absences, myoclonic and atonic seizures); Gastaut Syndrome Lennox-;
- For the treatment of partial seizures (partial seizures with secondary generalization or not).
For children, as monotherapy or in combination with other antiepileptic drugs:
- For the treatment of generalized seizures (clonic, tonic, tonic-clonic seizures, absences, myoclonic and atonic seizures); Gastaut Syndrome Lennox-;
- For the treatment of partial seizures (partial seizures with secondary generalization or not).
Treatment of mania in bipolar disorder syndrome.
 

Contraindications

Hypersensitivity to valproate, dyvalproatu, valpromidu or to any component of the drug in history.
Acute hepatitis.
Chronic hepatitis.
Cases of severe hepatitis in an individual or a family history of the patient, especially caused by drugs.
Hepatic porphyria.
The combination of mefloquine and St. John's wort extract. 
Children weighing less than 17 kg.

Children under 6 years (in connection with the risks of the pill in the airway during swallowing).

Dosage & Administration

Depakin is a form of the drug Depakin sustained release of the active ingredient which allows to reduce maximum concentration of active ingredient in the blood plasma and provides more uniform drug concentrations in plasma throughout the day.

Choosing dose should be aware that this drug is prescribed for adults and children weighing more than 17 kg.
This dosage form does not apply to children under 6 years (risk of falling pills in the airway during swallowing).

Dosage
Treatment of epilepsy.

The initial daily dose is usually 10-15 mg / kg, then it increased to achieve optimal doses (see. See "Getting treatment").
The average daily dose is 20-30 mg / kg. However, if uncontrolled epilepsy are at these doses can be increased by careful observation of the patient.
For children the usual dose is 30 mg / kg per day.
For adult - usual dose is 20-30 mg / kg per day.