Details
Amitriptylin Indications
- depression different etiology (endogenous, involutional, reactive, neurotic, medication);
- neurotic states with a predominant depressive symptoms;
- depression in patients with schizophrenia (in combination with a neuroleptic);
- chronic pain syndrome;
- nocturnal enuresis in the absence of organic pathology;
- headache, migraine (prevention).
Dosage & Administration
The tablets are taken orally without chewing, immediately after a meal (to reduce irritation of the gastric mucosa).
Depression
It is necessary to begin treatment with the use of low doses with a gradual increase in their under constant observation of clinical effect and tolerability. Dosages above 150 mg daily preferably administered hospitalized patients.
Adults
First, 25 mg 3 times per day with gradual increase, if necessary, on each subsequent day of 25 mg to 150 mg level (in some cases - to 25 mg per day hospitalized patients). The additional amount of the drug is prescribed mainly in the evening.
Podderzhivayuschaaya meets the optimal therapeutic dose.
Teens and patients older than 65 years. First, 10 mg 3 times per day with gradual increase, if necessary, every other day to a level 100 - 150 mg per day. The additional amount of the drug is prescribed mainly in the evening.
Maintenance dose corresponds to optimal therapeutic.
Children
Treatment of children is permitted only in a hospital.
For the treatment of enuresis in children dose picked individually.
Starting dose - 1.5 mg / kg per day rising weekly with 1.5 mg / kg per day to a maximum of - 5 mg / kg per day.
The duration of therapy. The antidepressant effect develops within 2 - 4 weeks.